Facile synthesis and antiproliferative activity of new 3-cyanopyridines

synthesis and characterization of some new cyclometalated organoplatinum(ii) complexes containing phosphite ligand

در این تحقیق روشی جهت سنتز یک سری از کمپلکس های پلاتین (ii) حاوی لیگاند های دهنده ی فسفری شامل فسفیت و فسفین ارائه شده است. واکنش پیش ماده ی پلاتین (ii)،trans/cis- [ptcl2(sme2)2] ، با 2 اکی مولار از لیگاند p(oph)3در حلال بنزن کمپلکس1، cis-[ptcl2(p(oph)3)2] را تولید می نماید. جهت سنتز کمپلکس سایکلو متال فسفیتی، کمپلکس 1 با 1 اکی والان واکنشگر ptcl2 در حلال زایلن در شرایط رفلاکس زیر گاز آرگون م...

Synthesis, antiproliferative evaluation, and structure-activity relationships of 3-arylquinolines.

Design, Synthesis and Evaluation of Antiproliferative Activity of New Benzimidazolehydrazones.

The synthesis and antiproliferative activity of new benzimidazole derivatives bearing an hydrazone mojety at the 2-position is described. The new N'-(4-arylidene)-1H-benzo[d]imidazole-2-carbohydrazides were evaluated for their cytostatic activity toward the murine leukemia (L1210), human T-cell leukemia (CEM), human cervix carcinoma (HeLa) and human pancreas carcinoma cells (Mia Paca-2). A prel...

Synthesis and antiproliferative activity of new tonantzitlolone-derived diterpene derivatives.

The synthesis of the diterpene (+)-tonantzitlolone A and a series of derivatives is reported. The study includes the determination of their antiproliferative activities against selected cancer cell lines.

Microwave-assisted synthesis of new selenazole derivatives with antiproliferative activity.

New aryl-hydrazinyl-1,3-selenazole and aroyl-hydrazonyl-1,3-selenazoles were synthesized via Hantzsch type condensation reactions of selenosemicarbazides with α-halogenocarbonyl derivatives, under classical versus microwave heating conditions. Excellent yields and shorter reaction times were obtained under irradiation conditions. The structures of the synthesized compounds were assigned based o...